Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1)
Homo sapiens — UniProt Q96EK6
Data last refreshed: (UniProt release unknown)
Key facts
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) is a protein from Homo sapiens identified by UniProt accession Q96EK6, 184 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q96EK6; gene symbol GNPNAT1.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): rhizomelic dysplasia, Ain-Naz type, protein measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glucosamine 6-phosphate N-acetyltransferase |
|---|---|
| UniProt accession | Q96EK6 |
| Gene | GNPNAT1 |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- rhizomelic dysplasia, Ain-Naz type · score 0.45
- protein measurement · score 0.30
- blood protein measurement · score 0.18
- lung adenocarcinoma · score 0.11
- Alzheimer disease · score 0.08
- family history of Alzheimer’s disease · score 0.08
- non-small cell lung carcinoma · score 0.08
- breast cancer · score 0.07
- neoplasm · score 0.07
- late-onset Alzheimers disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EK6-F1 | alphafold | PREDICTED | 97.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EK6.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GNPNAT1?
The strongest Open Targets associations for GNPNAT1 are rhizomelic dysplasia, Ain-Naz type, protein measurement, blood protein measurement, lung adenocarcinoma and Alzheimer disease.
How long is the GNPNAT1 protein?
The Homo sapiens GNPNAT1 protein (UniProt Q96EK6) is 184 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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