Constitutive coactivator of peroxisome proliferator-activated receptor gamma (FAM120B)
Homo sapiens — UniProt Q96EK7
Data last refreshed: (UniProt release unknown)
Key facts
Constitutive coactivator of peroxisome proliferator-activated receptor gamma (FAM120B) is a protein from Homo sapiens identified by UniProt accession Q96EK7, 910 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q96EK7; gene symbol FAM120B.
- Organism: Homo sapiens.
- Length: 910 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Constitutive coactivator of peroxisome proliferator-activated receptor gamma |
|---|---|
| UniProt accession | Q96EK7 |
| Gene | FAM120B |
| Organism | Homo sapiens |
| Length | 910 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- blood protein measurement · score 0.26
- platelet count · score 0.25
- vein disorder · score 0.25
- hemoglobin measurement · score 0.24
- erythrocyte count · score 0.23
- daytime rest measurement · score 0.23
- risk-taking behaviour · score 0.22
- monocyte count · score 0.22
- hematocrit · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EK7-F1 | alphafold | PREDICTED | 71.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EK7.
Amino-acid sequence (910 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM120B?
The strongest Open Targets associations for FAM120B are neurodegenerative disease, blood protein measurement, platelet count, vein disorder and hemoglobin measurement.
How long is the FAM120B protein?
The Homo sapiens FAM120B protein (UniProt Q96EK7) is 910 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EK7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EK7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.