Small glutamine-rich tetratricopeptide repeat-containing protein beta (SGTB)
Homo sapiens — UniProt Q96EQ0
Data last refreshed: (UniProt release unknown)
Key facts
Small glutamine-rich tetratricopeptide repeat-containing protein beta (SGTB) is a protein from Homo sapiens identified by UniProt accession Q96EQ0, 304 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q96EQ0; gene symbol SGTB.
- Organism: Homo sapiens.
- Length: 304 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte count and thalamus volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small glutamine-rich tetratricopeptide repeat-containing protein beta |
|---|---|
| UniProt accession | Q96EQ0 |
| Gene | SGTB |
| Organism | Homo sapiens |
| Length | 304 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- reticulocyte count · score 0.21
- thalamus volume · score 0.18
- neuroimaging measurement · score 0.15
- reticulocyte measurement · score 0.15
- brain volume measurement · score 0.15
- brain measurement · score 0.13
- brain stem volume measurement · score 0.13
- refractive error measurement · score 0.08
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EQ0-F1 | alphafold | PREDICTED | 81.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EQ0.
Amino-acid sequence (304 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SGTB?
The strongest Open Targets associations for SGTB are neurodegenerative disease, reticulocyte count, thalamus volume, neuroimaging measurement and reticulocyte measurement.
How long is the SGTB protein?
The Homo sapiens SGTB protein (UniProt Q96EQ0) is 304 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.