Solute carrier family 33 member 2 (SLC33A2)
Homo sapiens — UniProt Q96ES6
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 33 member 2 (SLC33A2) is a protein from Homo sapiens identified by UniProt accession Q96ES6, 412 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q96ES6; gene symbol SLC33A2.
- Organism: Homo sapiens.
- Length: 412 amino acids.
- Top disease associations (Open Targets): serum alanine aminotransferase measurement, cataract and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 33 member 2 |
|---|---|
| UniProt accession | Q96ES6 |
| Gene | SLC33A2 |
| Organism | Homo sapiens |
| Length | 412 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.13
- cataract · score 0.11
- Red cell distribution width · score 0.06
- mean corpuscular hemoglobin concentration · score 0.05
- self reported educational attainment · score 0.04
- intelligence · score 0.03
- cognitive function measurement · score 0.03
- Lewy body dementia · score 0.02
- Crohn's disease · score 0.01
- ovarian carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96ES6-F1 | alphafold | PREDICTED | 89.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96ES6.
Amino-acid sequence (412 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC33A2?
The strongest Open Targets associations for SLC33A2 are serum alanine aminotransferase measurement, cataract, Red cell distribution width, mean corpuscular hemoglobin concentration and self reported educational attainment.
How long is the SLC33A2 protein?
The Homo sapiens SLC33A2 protein (UniProt Q96ES6) is 412 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96ES6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96ES6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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