DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3)
Homo sapiens — UniProt Q96EY1
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3) is a protein from Homo sapiens identified by UniProt accession Q96EY1, 480 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q96EY1; gene symbol DNAJA3.
- Organism: Homo sapiens.
- Length: 480 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte count and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily A member 3, mitochondrial |
|---|---|
| UniProt accession | Q96EY1 |
| Gene | DNAJA3 |
| Organism | Homo sapiens |
| Length | 480 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- reticulocyte count · score 0.27
- schizophrenia · score 0.26
- BMI-adjusted waist-hip ratio · score 0.22
- pulse pressure measurement · score 0.21
- leukocyte count · score 0.21
- reticulocyte measurement · score 0.20
- waist-hip ratio · score 0.19
- triglyceride measurement · score 0.18
- migraine disorder · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EY1-F1 | alphafold | PREDICTED | 74.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EY1.
Amino-acid sequence (480 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJA3?
The strongest Open Targets associations for DNAJA3 are neurodegenerative disease, reticulocyte count, schizophrenia, BMI-adjusted waist-hip ratio and pulse pressure measurement.
How long is the DNAJA3 protein?
The Homo sapiens DNAJA3 protein (UniProt Q96EY1) is 480 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EY1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EY1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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