Microspherule protein 1 (MCRS1)
Homo sapiens — UniProt Q96EZ8
Data last refreshed: (UniProt release unknown)
Key facts
Microspherule protein 1 (MCRS1) is a protein from Homo sapiens identified by UniProt accession Q96EZ8, 462 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q96EZ8; gene symbol MCRS1.
- Organism: Homo sapiens.
- Length: 462 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, clear cell renal carcinoma and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Microspherule protein 1 |
|---|---|
| UniProt accession | Q96EZ8 |
| Gene | MCRS1 |
| Organism | Homo sapiens |
| Length | 462 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.26
- clear cell renal carcinoma · score 0.10
- non-small cell lung carcinoma · score 0.09
- neoplasm · score 0.09
- pulse pressure measurement · score 0.09
- smoking status measurement · score 0.09
- systolic blood pressure · score 0.09
- hypertension · score 0.09
- attention deficit hyperactivity disorder · score 0.08
- glioma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96EZ8-F1 | alphafold | PREDICTED | 74.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96EZ8.
Amino-acid sequence (462 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MCRS1?
The strongest Open Targets associations for MCRS1 are breast adenocarcinoma, clear cell renal carcinoma, non-small cell lung carcinoma, neoplasm and pulse pressure measurement.
How long is the MCRS1 protein?
The Homo sapiens MCRS1 protein (UniProt Q96EZ8) is 462 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96EZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96EZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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