Polypeptide N-acetylgalactosaminyltransferase 14 (GALNT14)
Homo sapiens — UniProt Q96FL9
Data last refreshed: (UniProt release unknown)
Key facts
Polypeptide N-acetylgalactosaminyltransferase 14 (GALNT14) is a protein from Homo sapiens identified by UniProt accession Q96FL9, 552 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q96FL9; gene symbol GALNT14.
- Organism: Homo sapiens.
- Length: 552 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Non-immune hydrops fetalis and eosinophilic esophagitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 14 |
|---|---|
| UniProt accession | Q96FL9 |
| Gene | GALNT14 |
| Organism | Homo sapiens |
| Length | 552 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- Non-immune hydrops fetalis · score 0.27
- eosinophilic esophagitis · score 0.15
- protein measurement · score 0.14
- glioblastoma multiforme · score 0.14
- volvulus of midgut · score 0.12
- Intestinal malrotation · score 0.12
- Familial intestinal malrotation - facial anomalies · score 0.12
- hepatocellular carcinoma · score 0.09
- breast cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96FL9-F1 | alphafold | PREDICTED | 89.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96FL9.
Amino-acid sequence (552 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT14?
The strongest Open Targets associations for GALNT14 are neurodegenerative disease, Non-immune hydrops fetalis, eosinophilic esophagitis, protein measurement and glioblastoma multiforme.
How long is the GALNT14 protein?
The Homo sapiens GALNT14 protein (UniProt Q96FL9) is 552 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96FL9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96FL9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.