Phospholipid phosphatase-related protein type 2 (PLPPR2)
Homo sapiens — UniProt Q96GM1
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipid phosphatase-related protein type 2 (PLPPR2) is a protein from Homo sapiens identified by UniProt accession Q96GM1, 343 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q96GM1; gene symbol PLPPR2.
- Organism: Homo sapiens.
- Length: 343 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, lipoprotein measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipid phosphatase-related protein type 2 |
|---|---|
| UniProt accession | Q96GM1 |
| Gene | PLPPR2 |
| Organism | Homo sapiens |
| Length | 343 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.24
- lipoprotein measurement · score 0.12
- platelet count · score 0.09
- hypertension · score 0.07
- coronary artery disease · score 0.04
- mean corpuscular volume · score 0.03
- neutrophil count · score 0.02
- mean corpuscular hemoglobin · score 0.02
- platelet crit · score 0.02
- low density lipoprotein cholesterol measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GM1-F1 | alphafold | PREDICTED | 79.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GM1.
Amino-acid sequence (343 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLPPR2?
The strongest Open Targets associations for PLPPR2 are diastolic blood pressure, lipoprotein measurement, platelet count, hypertension and coronary artery disease.
How long is the PLPPR2 protein?
The Homo sapiens PLPPR2 protein (UniProt Q96GM1) is 343 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GM1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GM1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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