RUS family member 1 (RUSF1)
Homo sapiens — UniProt Q96GQ5
Data last refreshed: (UniProt release unknown)
Key facts
RUS family member 1 (RUSF1) is a protein from Homo sapiens identified by UniProt accession Q96GQ5, 468 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q96GQ5; gene symbol RUSF1.
- Organism: Homo sapiens.
- Length: 468 amino acids.
- Top disease associations (Open Targets): familial renal glucosuria, genetic disorder and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RUS family member 1 |
|---|---|
| UniProt accession | Q96GQ5 |
| Gene | RUSF1 |
| Organism | Homo sapiens |
| Length | 468 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- familial renal glucosuria · score 0.20
- genetic disorder · score 0.17
- mean corpuscular hemoglobin concentration · score 0.14
- parental genotype effect measurement · score 0.11
- gestational blood glucose measurement · score 0.11
- Glycosuria · score 0.11
- fetal genotype effect measurement · score 0.08
- mean corpuscular hemoglobin · score 0.04
- mean corpuscular volume · score 0.03
- platelet count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GQ5-F1 | alphafold | PREDICTED | 85.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GQ5.
Amino-acid sequence (468 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RUSF1?
The strongest Open Targets associations for RUSF1 are familial renal glucosuria, genetic disorder, mean corpuscular hemoglobin concentration, parental genotype effect measurement and gestational blood glucose measurement.
How long is the RUSF1 protein?
The Homo sapiens RUSF1 protein (UniProt Q96GQ5) is 468 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GQ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GQ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.