Brevican core protein (BCAN)
Homo sapiens — UniProt Q96GW7
Data last refreshed: (UniProt release unknown)
Key facts
Brevican core protein (BCAN) is a protein from Homo sapiens identified by UniProt accession Q96GW7, 911 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q96GW7; gene symbol BCAN.
- Organism: Homo sapiens.
- Length: 911 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, ovarian cancer and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Brevican core protein |
|---|---|
| UniProt accession | Q96GW7 |
| Gene | BCAN |
| Organism | Homo sapiens |
| Length | 911 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- ovarian cancer · score 0.25
- breast adenocarcinoma · score 0.24
- blood protein measurement · score 0.24
- cutaneous melanoma · score 0.20
- acute myeloid leukemia · score 0.15
- gastric adenocarcinoma · score 0.14
- Myopia · score 0.11
- pathological myopia · score 0.11
- neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GW7-F1 | alphafold | PREDICTED | 68.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GW7.
Amino-acid sequence (911 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BCAN?
The strongest Open Targets associations for BCAN are neurodegenerative disease, ovarian cancer, breast adenocarcinoma, blood protein measurement and cutaneous melanoma.
How long is the BCAN protein?
The Homo sapiens BCAN protein (UniProt Q96GW7) is 911 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.