Uncharacterized protein C16orf74 (C16orf74)
Homo sapiens — UniProt Q96GX8
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C16orf74 (C16orf74) is a protein from Homo sapiens identified by UniProt accession Q96GX8, 76 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q96GX8; gene symbol C16orf74.
- Organism: Homo sapiens.
- Length: 76 amino acids.
- Top disease associations (Open Targets): eosinophil percentage of leukocytes, neutrophil count and monocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C16orf74 |
|---|---|
| UniProt accession | Q96GX8 |
| Gene | C16orf74 |
| Organism | Homo sapiens |
| Length | 76 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- eosinophil percentage of leukocytes · score 0.28
- neutrophil count · score 0.18
- monocyte percentage of leukocytes · score 0.16
- eosinophil count · score 0.15
- alcohol consumption measurement · score 0.14
- alcohol use disorder measurement · score 0.11
- sum of eosinophil and basophil counts · score 0.10
- monocyte count · score 0.07
- serum gamma-glutamyl transferase measurement · score 0.07
- adolescent idiopathic scoliosis · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GX8-F1 | alphafold | PREDICTED | 68.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GX8.
Amino-acid sequence (76 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C16orf74?
The strongest Open Targets associations for C16orf74 are eosinophil percentage of leukocytes, neutrophil count, monocyte percentage of leukocytes, eosinophil count and alcohol consumption measurement.
How long is the C16orf74 protein?
The Homo sapiens C16orf74 protein (UniProt Q96GX8) is 76 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GX8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GX8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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