Methylthioribulose-1-phosphate dehydratase (APIP)
Homo sapiens — UniProt Q96GX9
Data last refreshed: (UniProt release unknown)
Key facts
Methylthioribulose-1-phosphate dehydratase (APIP) is a protein from Homo sapiens identified by UniProt accession Q96GX9, 242 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q96GX9; gene symbol APIP.
- Organism: Homo sapiens.
- Length: 242 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, FEV/FVC ratio and CC16 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Methylthioribulose-1-phosphate dehydratase |
|---|---|
| UniProt accession | Q96GX9 |
| Gene | APIP |
| Organism | Homo sapiens |
| Length | 242 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.34
- FEV/FVC ratio · score 0.28
- CC16 measurement · score 0.26
- cystic fibrosis · score 0.25
- blood protein measurement · score 0.23
- serum gamma-glutamyl transferase measurement · score 0.23
- chronic obstructive pulmonary disease · score 0.21
- glucose measurement · score 0.21
- HbA1c measurement · score 0.20
- pyruvate dehydrogenase E3-binding protein deficiency · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GX9-F1 | alphafold | PREDICTED | 92.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GX9.
Amino-acid sequence (242 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with APIP?
The strongest Open Targets associations for APIP are type 2 diabetes mellitus, FEV/FVC ratio, CC16 measurement, cystic fibrosis and blood protein measurement.
How long is the APIP protein?
The Homo sapiens APIP protein (UniProt Q96GX9) is 242 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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