Solute carrier family 41 member 3 (SLC41A3)
Homo sapiens — UniProt Q96GZ6
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 41 member 3 (SLC41A3) is a protein from Homo sapiens identified by UniProt accession Q96GZ6, 507 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q96GZ6; gene symbol SLC41A3.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, Autosomal dominant primary hypomagnesemia with hypocalciuria and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 41 member 3 |
|---|---|
| UniProt accession | Q96GZ6 |
| Gene | SLC41A3 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.09
- Autosomal dominant primary hypomagnesemia with hypocalciuria · score 0.08
- cancer · score 0.08
- Primary hypomagnesemia with secondary hypocalcemia · score 0.07
- glycine measurement · score 0.06
- neoplasm · score 0.05
- Benign familial chorea · score 0.05
- congenital hydronephrosis · score 0.05
- familial vesicoureteral reflux · score 0.05
- Familial isolated hypoparathyroidism · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96GZ6-F1 | alphafold | PREDICTED | 79.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96GZ6.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC41A3?
The strongest Open Targets associations for SLC41A3 are hepatocellular carcinoma, Autosomal dominant primary hypomagnesemia with hypocalciuria, cancer, Primary hypomagnesemia with secondary hypocalcemia and glycine measurement.
How long is the SLC41A3 protein?
The Homo sapiens SLC41A3 protein (UniProt Q96GZ6) is 507 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96GZ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96GZ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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