Proline-rich protein 11 (PRR11)
Homo sapiens — UniProt Q96HE9
Data last refreshed: (UniProt release unknown)
Key facts
Proline-rich protein 11 (PRR11) is a protein from Homo sapiens identified by UniProt accession Q96HE9, 360 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q96HE9; gene symbol PRR11.
- Organism: Homo sapiens.
- Length: 360 amino acids.
- Top disease associations (Open Targets): type 1 diabetes mellitus, neoplasm and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline-rich protein 11 |
|---|---|
| UniProt accession | Q96HE9 |
| Gene | PRR11 |
| Organism | Homo sapiens |
| Length | 360 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- type 1 diabetes mellitus · score 0.20
- neoplasm · score 0.11
- non-small cell lung carcinoma · score 0.10
- cancer · score 0.09
- esophageal squamous cell carcinoma · score 0.09
- myeloperoxidase measurement · score 0.08
- lung adenocarcinoma · score 0.08
- bladder transitional cell carcinoma · score 0.08
- hypotonia-cystinuria syndrome · score 0.07
- Hypotonia - cystinuria syndrome · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HE9-F1 | alphafold | PREDICTED | 66.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HE9.
Amino-acid sequence (360 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRR11?
The strongest Open Targets associations for PRR11 are type 1 diabetes mellitus, neoplasm, non-small cell lung carcinoma, cancer and esophageal squamous cell carcinoma.
How long is the PRR11 protein?
The Homo sapiens PRR11 protein (UniProt Q96HE9) is 360 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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