Small integral membrane protein 10 (SMIM10)
Homo sapiens — UniProt Q96HG1
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 10 (SMIM10) is a protein from Homo sapiens identified by UniProt accession Q96HG1, 83 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q96HG1; gene symbol SMIM10.
- Organism: Homo sapiens.
- Length: 83 amino acids.
- Top disease associations (Open Targets): colorectal cancer, melanoma and dry eye syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 10 |
|---|---|
| UniProt accession | Q96HG1 |
| Gene | SMIM10 |
| Organism | Homo sapiens |
| Length | 83 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.01
- melanoma · score 0.01
- dry eye syndrome · score 0.01
- cancer · score 0.00
- Adams-Oliver syndrome · score 0.00
- visceral Leishmaniasis · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HG1-F1 | alphafold | PREDICTED | 66.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HG1.
Amino-acid sequence (83 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM10?
The strongest Open Targets associations for SMIM10 are colorectal cancer, melanoma, dry eye syndrome, cancer and Adams-Oliver syndrome.
How long is the SMIM10 protein?
The Homo sapiens SMIM10 protein (UniProt Q96HG1) is 83 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HG1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HG1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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