Coiled-coil domain-containing protein 34 (CCDC34)
Homo sapiens — UniProt Q96HJ3
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 34 (CCDC34) is a protein from Homo sapiens identified by UniProt accession Q96HJ3, 373 residues long. MolForge cross-references it against 0 known binders and 134 disease associations.
- UniProt accession: Q96HJ3; gene symbol CCDC34.
- Organism: Homo sapiens.
- Length: 373 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and male infertility with azoospermia or oligozoospermia due to single gene mutation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 34 |
|---|---|
| UniProt accession | Q96HJ3 |
| Gene | CCDC34 |
| Organism | Homo sapiens |
| Length | 373 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (134)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.53
- bone quantitative ultrasound measurement · score 0.47
- male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.38
- bone density · score 0.31
- hair colour measurement · score 0.26
- systolic blood pressure · score 0.26
- diabetes mellitus · score 0.26
- cystatin C measurement · score 0.25
- hair color · score 0.24
- hair shape measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HJ3-F1 | alphafold | PREDICTED | 68.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HJ3.
Amino-acid sequence (373 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC34?
The strongest Open Targets associations for CCDC34 are heel bone mineral density, bone quantitative ultrasound measurement, male infertility with azoospermia or oligozoospermia due to single gene mutation, bone density and hair colour measurement.
How long is the CCDC34 protein?
The Homo sapiens CCDC34 protein (UniProt Q96HJ3) is 373 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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