SH3 domain-containing YSC84-like protein 1 (SH3YL1)
Homo sapiens — UniProt Q96HL8
Data last refreshed: (UniProt release unknown)
Key facts
SH3 domain-containing YSC84-like protein 1 (SH3YL1) is a protein from Homo sapiens identified by UniProt accession Q96HL8, 342 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q96HL8; gene symbol SH3YL1.
- Organism: Homo sapiens.
- Length: 342 amino acids.
- Top disease associations (Open Targets): body height, low molecular weight phosphotyrosine protein phosphatase measurement and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SH3 domain-containing YSC84-like protein 1 |
|---|---|
| UniProt accession | Q96HL8 |
| Gene | SH3YL1 |
| Organism | Homo sapiens |
| Length | 342 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- body height · score 0.34
- low molecular weight phosphotyrosine protein phosphatase measurement · score 0.31
- serum gamma-glutamyl transferase measurement · score 0.29
- creatinine measurement · score 0.29
- high density lipoprotein cholesterol measurement · score 0.26
- cystatin C measurement · score 0.25
- body mass index · score 0.25
- refractive error · score 0.24
- serum urea measurement · score 0.24
- apolipoprotein A 1 measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HL8-F1 | alphafold | PREDICTED | 72.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HL8.
Amino-acid sequence (342 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SH3YL1?
The strongest Open Targets associations for SH3YL1 are body height, low molecular weight phosphotyrosine protein phosphatase measurement, serum gamma-glutamyl transferase measurement, creatinine measurement and high density lipoprotein cholesterol measurement.
How long is the SH3YL1 protein?
The Homo sapiens SH3YL1 protein (UniProt Q96HL8) is 342 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HL8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HL8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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