Receptor expression-enhancing protein 6 (REEP6)
Homo sapiens — UniProt Q96HR9
Data last refreshed: (UniProt release unknown)
Key facts
Receptor expression-enhancing protein 6 (REEP6) is a protein from Homo sapiens identified by UniProt accession Q96HR9, 211 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q96HR9; gene symbol REEP6.
- Organism: Homo sapiens.
- Length: 211 amino acids.
- Top disease associations (Open Targets): retinitis pigmentosa, inherited retinal dystrophy and autosomal recessive retinitis pigmentosa.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Receptor expression-enhancing protein 6 |
|---|---|
| UniProt accession | Q96HR9 |
| Gene | REEP6 |
| Organism | Homo sapiens |
| Length | 211 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- retinitis pigmentosa · score 0.68
- inherited retinal dystrophy · score 0.37
- autosomal recessive retinitis pigmentosa · score 0.34
- genetic disorder · score 0.19
- Retinal dystrophy · score 0.15
- azoospermia · score 0.06
- spermatogenic failure 65 · score 0.04
- spermatogenic failure 56 · score 0.04
- Crohn's disease · score 0.04
- spermatogenic failure 51 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HR9-F1 | alphafold | PREDICTED | 73.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HR9.
Amino-acid sequence (211 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with REEP6?
The strongest Open Targets associations for REEP6 are retinitis pigmentosa, inherited retinal dystrophy, autosomal recessive retinitis pigmentosa, genetic disorder and Retinal dystrophy.
How long is the REEP6 protein?
The Homo sapiens REEP6 protein (UniProt Q96HR9) is 211 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HR9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HR9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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