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Transmembrane protein 41A (TMEM41A)

Homo sapiens — UniProt Q96HV5

Gene: TMEM41AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transmembrane protein 41A (TMEM41A) is a protein from Homo sapiens identified by UniProt accession Q96HV5, 264 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q96HV5; gene symbol TMEM41A.
  • Organism: Homo sapiens.
  • Length: 264 amino acids.
  • Top disease associations (Open Targets): body height, PHF-tau measurement and cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTransmembrane protein 41A
UniProt accessionQ96HV5
GeneTMEM41A
OrganismHomo sapiens
Length264 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • body height · score 0.06
  • PHF-tau measurement · score 0.06
  • cancer · score 0.03
  • neoplasm · score 0.02
  • gonorrhea · score 0.01
  • diabetes mellitus · score 0.01
  • endometrial carcinoma · score 0.01
  • Flavivirus Infections · score 0.01
  • carcinoma · score 0.00
  • squamous cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96HV5-F1alphafoldPREDICTED84.30—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HV5.

Amino-acid sequence (264 residues)

MRPLLGLLLV FAGCTFALYL LSTRLPRGRR LGSTEEAGGR SLWFPSDLAE LRELSEVLRE YRKEHQAYVF LLFCGAYLYK QGFAIPGSSF LNVLAGALFG PWLGLLLCCV LTSVGATCCY LLSSIFGKQL VVSYFPDKVA LLQRKVEENR NSLFFFLLFL RLFPMTPNWF LNLSAPILNI PIVQFFFSVL IGLIPYNFIC VQTGSILSTL TSLDALFSWD TVFKLLAIAM VALIPGTLIK KFSQKHLQLN ETSTANHIHS RKDT

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TMEM41A?

The strongest Open Targets associations for TMEM41A are body height, PHF-tau measurement, cancer, neoplasm and gonorrhea.

How long is the TMEM41A protein?

The Homo sapiens TMEM41A protein (UniProt Q96HV5) is 264 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96HV5
GeneTMEM41A
OrganismHomo sapiens
Length264
Binders0
Diseases15
View on UniProt