Integrator complex subunit 4 (INTS4)
Homo sapiens — UniProt Q96HW7
Data last refreshed: (UniProt release unknown)
Key facts
Integrator complex subunit 4 (INTS4) is a protein from Homo sapiens identified by UniProt accession Q96HW7, 963 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q96HW7; gene symbol INTS4.
- Organism: Homo sapiens.
- Length: 963 amino acids.
- Top disease associations (Open Targets): platelet count, mean reticulocyte volume and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Integrator complex subunit 4 |
|---|---|
| UniProt accession | Q96HW7 |
| Gene | INTS4 |
| Organism | Homo sapiens |
| Length | 963 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- platelet count · score 0.25
- mean reticulocyte volume · score 0.17
- sex hormone-binding globulin measurement · score 0.16
- mean platelet volume · score 0.13
- hepatocellular carcinoma · score 0.07
- Red cell distribution width · score 0.04
- body height · score 0.04
- neoplasm · score 0.04
- diastolic blood pressure · score 0.03
- handedness · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96HW7-F1 | alphafold | PREDICTED | 83.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96HW7.
Amino-acid sequence (963 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INTS4?
The strongest Open Targets associations for INTS4 are platelet count, mean reticulocyte volume, sex hormone-binding globulin measurement, mean platelet volume and hepatocellular carcinoma.
How long is the INTS4 protein?
The Homo sapiens INTS4 protein (UniProt Q96HW7) is 963 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96HW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96HW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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