Protein ABHD8 (ABHD8)
Homo sapiens — UniProt Q96I13
Data last refreshed: (UniProt release unknown)
Key facts
Protein ABHD8 (ABHD8) is a protein from Homo sapiens identified by UniProt accession Q96I13, 439 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q96I13; gene symbol ABHD8.
- Organism: Homo sapiens.
- Length: 439 amino acids.
- Top disease associations (Open Targets): mitochondrial DNA measurement, breast carcinoma and estrogen-receptor negative breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein ABHD8 |
|---|---|
| UniProt accession | Q96I13 |
| Gene | ABHD8 |
| Organism | Homo sapiens |
| Length | 439 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- mitochondrial DNA measurement · score 0.18
- breast carcinoma · score 0.18
- estrogen-receptor negative breast cancer · score 0.18
- ovarian carcinoma · score 0.17
- ovarian serous carcinoma · score 0.17
- HbA1c measurement · score 0.13
- low density lipoprotein cholesterol measurement · score 0.13
- squamous cell lung carcinoma · score 0.12
- lung adenocarcinoma · score 0.12
- lung carcinoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96I13-F1 | alphafold | PREDICTED | 78.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96I13.
Amino-acid sequence (439 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABHD8?
The strongest Open Targets associations for ABHD8 are mitochondrial DNA measurement, breast carcinoma, estrogen-receptor negative breast cancer, ovarian carcinoma and ovarian serous carcinoma.
How long is the ABHD8 protein?
The Homo sapiens ABHD8 protein (UniProt Q96I13) is 439 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96I13 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96I13 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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