Splicing factor 45 (RBM17)
Homo sapiens — UniProt Q96I25
Data last refreshed: (UniProt release unknown)
Key facts
Splicing factor 45 (RBM17) is a protein from Homo sapiens identified by UniProt accession Q96I25, 401 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q96I25; gene symbol RBM17.
- Organism: Homo sapiens.
- Length: 401 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lymphocyte count and serum non-albumin protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Splicing factor 45 |
|---|---|
| UniProt accession | Q96I25 |
| Gene | RBM17 |
| Organism | Homo sapiens |
| Length | 401 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- lymphocyte count · score 0.32
- serum non-albumin protein measurement · score 0.22
- blood protein measurement · score 0.22
- multiple sclerosis · score 0.21
- total blood protein measurement · score 0.21
- hypothyroidism · score 0.21
- soluble interleukin-2 receptor subunit alpha measurement · score 0.20
- PHF-tau measurement · score 0.19
- type 1 diabetes mellitus · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96I25-F1 | alphafold | PREDICTED | 68.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96I25.
Amino-acid sequence (401 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBM17?
The strongest Open Targets associations for RBM17 are neurodegenerative disease, lymphocyte count, serum non-albumin protein measurement, blood protein measurement and multiple sclerosis.
How long is the RBM17 protein?
The Homo sapiens RBM17 protein (UniProt Q96I25) is 401 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96I25 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96I25 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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