RCC1-like G exchanging factor-like protein (RCC1L)
Homo sapiens — UniProt Q96I51
Data last refreshed: (UniProt release unknown)
Key facts
RCC1-like G exchanging factor-like protein (RCC1L) is a protein from Homo sapiens identified by UniProt accession Q96I51, 464 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q96I51; gene symbol RCC1L.
- Organism: Homo sapiens.
- Length: 464 amino acids.
- Top disease associations (Open Targets): lymphocyte count, 22q11.2 deletion syndrome and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RCC1-like G exchanging factor-like protein |
|---|---|
| UniProt accession | Q96I51 |
| Gene | RCC1L |
| Organism | Homo sapiens |
| Length | 464 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.05
- 22q11.2 deletion syndrome · score 0.04
- hypertension · score 0.04
- lean body mass · score 0.03
- lymphocyte percentage of leukocytes · score 0.03
- X-Linked Combined Immunodeficiency Diseases · score 0.03
- IGF-1 measurement · score 0.02
- body weight · score 0.02
- body fat percentage · score 0.02
- base metabolic rate measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96I51-F1 | alphafold | PREDICTED | 89.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96I51.
Amino-acid sequence (464 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RCC1L?
The strongest Open Targets associations for RCC1L are lymphocyte count, 22q11.2 deletion syndrome, hypertension, lean body mass and lymphocyte percentage of leukocytes.
How long is the RCC1L protein?
The Homo sapiens RCC1L protein (UniProt Q96I51) is 464 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96I51 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96I51 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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