Vesicle-trafficking protein SEC22a (SEC22A)
Homo sapiens — UniProt Q96IW7
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle-trafficking protein SEC22a (SEC22A) is a protein from Homo sapiens identified by UniProt accession Q96IW7, 307 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q96IW7; gene symbol SEC22A.
- Organism: Homo sapiens.
- Length: 307 amino acids.
- Top disease associations (Open Targets): body height, pancreatic adenocarcinoma and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle-trafficking protein SEC22a |
|---|---|
| UniProt accession | Q96IW7 |
| Gene | SEC22A |
| Organism | Homo sapiens |
| Length | 307 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- body height · score 0.29
- pancreatic adenocarcinoma · score 0.21
- appendicular lean mass · score 0.11
- breast adenocarcinoma · score 0.10
- fibrinogen measurement · score 0.07
- platelet count · score 0.05
- blood protein measurement · score 0.05
- platelet crit · score 0.05
- type 2 diabetes mellitus · score 0.05
- mean platelet volume · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96IW7-F1 | alphafold | PREDICTED | 82.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96IW7.
Amino-acid sequence (307 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SEC22A?
The strongest Open Targets associations for SEC22A are body height, pancreatic adenocarcinoma, appendicular lean mass, breast adenocarcinoma and fibrinogen measurement.
How long is the SEC22A protein?
The Homo sapiens SEC22A protein (UniProt Q96IW7) is 307 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96IW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96IW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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