Carboxypeptidase B2 (CPB2)
Homo sapiens — UniProt Q96IY4
Data last refreshed: (UniProt release unknown)
Key facts
Carboxypeptidase B2 (CPB2) is a protein from Homo sapiens identified by UniProt accession Q96IY4, 423 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.
- UniProt accession: Q96IY4; gene symbol CPB2.
- Organism: Homo sapiens.
- Length: 423 amino acids.
- Top disease associations (Open Targets): blood protein measurement, carboxypeptidase B2 measurement and MAP kinase-activated protein kinase 3 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carboxypeptidase B2 |
|---|---|
| UniProt accession | Q96IY4 |
| Gene | CPB2 |
| Organism | Homo sapiens |
| Length | 423 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (164)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.50
- carboxypeptidase B2 measurement · score 0.42
- MAP kinase-activated protein kinase 3 measurement · score 0.38
- protein measurement · score 0.36
- angiostatin measurement · score 0.29
- thrombin activatable fibrinolysis inhibitor activation peptide measurement · score 0.22
- endometrial cancer · score 0.18
- lymphocyte count · score 0.15
- cutaneous melanoma · score 0.13
- macrophage migration inhibitory factor measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96IY4-F1 | alphafold | PREDICTED | 94.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96IY4.
Amino-acid sequence (423 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CPB2?
The strongest Open Targets associations for CPB2 are blood protein measurement, carboxypeptidase B2 measurement, MAP kinase-activated protein kinase 3 measurement, protein measurement and angiostatin measurement.
How long is the CPB2 protein?
The Homo sapiens CPB2 protein (UniProt Q96IY4) is 423 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96IY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96IY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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