Cysteine and tyrosine-rich protein 1 (CYYR1)
Homo sapiens — UniProt Q96J86
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine and tyrosine-rich protein 1 (CYYR1) is a protein from Homo sapiens identified by UniProt accession Q96J86, 154 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q96J86; gene symbol CYYR1.
- Organism: Homo sapiens.
- Length: 154 amino acids.
- Top disease associations (Open Targets): viral load, neurofibrillary tangles measurement and venous thromboembolism.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine and tyrosine-rich protein 1 |
|---|---|
| UniProt accession | Q96J86 |
| Gene | CYYR1 |
| Organism | Homo sapiens |
| Length | 154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- viral load · score 0.28
- neurofibrillary tangles measurement · score 0.23
- venous thromboembolism · score 0.10
- protein measurement · score 0.06
- neoplasm · score 0.05
- diabetes mellitus · score 0.04
- hair colour measurement · score 0.04
- DNA methylation · score 0.03
- PHF-tau measurement · score 0.03
- visual perception measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96J86-F1 | alphafold | PREDICTED | 60.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96J86.
Amino-acid sequence (154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYYR1?
The strongest Open Targets associations for CYYR1 are viral load, neurofibrillary tangles measurement, venous thromboembolism, protein measurement and neoplasm.
How long is the CYYR1 protein?
The Homo sapiens CYYR1 protein (UniProt Q96J86) is 154 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96J86 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96J86 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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