Epithelial-stromal interaction protein 1 (EPSTI1)
Homo sapiens — UniProt Q96J88
Data last refreshed: (UniProt release unknown)
Key facts
Epithelial-stromal interaction protein 1 (EPSTI1) is a protein from Homo sapiens identified by UniProt accession Q96J88, 318 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q96J88; gene symbol EPSTI1.
- Organism: Homo sapiens.
- Length: 318 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, chronic venous insufficiency and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Epithelial-stromal interaction protein 1 |
|---|---|
| UniProt accession | Q96J88 |
| Gene | EPSTI1 |
| Organism | Homo sapiens |
| Length | 318 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.44
- chronic venous insufficiency · score 0.27
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- neoplasm · score 0.07
- oral squamous cell carcinoma · score 0.06
- coagulation factor measurement · score 0.05
- eosinophil peroxidase deficiency · score 0.05
- neutropenia-monocytopenia-deafness syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96J88-F1 | alphafold | PREDICTED | 73.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96J88.
Amino-acid sequence (318 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EPSTI1?
The strongest Open Targets associations for EPSTI1 are heel bone mineral density, chronic venous insufficiency, prostate carcinoma, prostate cancer and Familial prostate cancer.
How long is the EPSTI1 protein?
The Homo sapiens EPSTI1 protein (UniProt Q96J88) is 318 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96J88 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96J88 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.