Protein transport protein Sec16B (SEC16B)
Homo sapiens — UniProt Q96JE7
Data last refreshed: (UniProt release unknown)
Key facts
Protein transport protein Sec16B (SEC16B) is a protein from Homo sapiens identified by UniProt accession Q96JE7, 1060 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.
- UniProt accession: Q96JE7; gene symbol SEC16B.
- Organism: Homo sapiens.
- Length: 1060 amino acids.
- Top disease associations (Open Targets): body mass index, alkaline phosphatase measurement and waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein transport protein Sec16B |
|---|---|
| UniProt accession | Q96JE7 |
| Gene | SEC16B |
| Organism | Homo sapiens |
| Length | 1060 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (81)
Diseases linked to this target (Open Targets).
- body mass index · score 0.50
- alkaline phosphatase measurement · score 0.48
- waist circumference · score 0.45
- lean body mass · score 0.45
- body fat percentage · score 0.45
- physical activity measurement · score 0.44
- fat body mass · score 0.43
- body weight · score 0.43
- smoking behavior · score 0.43
- body fat distribution · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JE7-F1 | alphafold | PREDICTED | 55.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JE7.
Amino-acid sequence (1060 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SEC16B?
The strongest Open Targets associations for SEC16B are body mass index, alkaline phosphatase measurement, waist circumference, lean body mass and body fat percentage.
How long is the SEC16B protein?
The Homo sapiens SEC16B protein (UniProt Q96JE7) is 1060 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JE7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JE7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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