Microtubule-associated protein 6 (MAP6)
Homo sapiens — UniProt Q96JE9
Data last refreshed: (UniProt release unknown)
Key facts
Microtubule-associated protein 6 (MAP6) is a protein from Homo sapiens identified by UniProt accession Q96JE9, 813 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q96JE9; gene symbol MAP6.
- Organism: Homo sapiens.
- Length: 813 amino acids.
- Top disease associations (Open Targets): metabolite measurement, Asperger syndrome and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Microtubule-associated protein 6 |
|---|---|
| UniProt accession | Q96JE9 |
| Gene | MAP6 |
| Organism | Homo sapiens |
| Length | 813 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.13
- Asperger syndrome · score 0.07
- attention deficit hyperactivity disorder · score 0.06
- childhood disintegrative disorder · score 0.05
- Potocki-Lupski syndrome · score 0.05
- autism · score 0.05
- schizophrenia · score 0.04
- Autism · score 0.04
- 15q11q13 microduplication syndrome · score 0.04
- high density lipoprotein cholesterol measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JE9-F1 | alphafold | PREDICTED | 47.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JE9.
Amino-acid sequence (813 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAP6?
The strongest Open Targets associations for MAP6 are metabolite measurement, Asperger syndrome, attention deficit hyperactivity disorder, childhood disintegrative disorder and Potocki-Lupski syndrome.
How long is the MAP6 protein?
The Homo sapiens MAP6 protein (UniProt Q96JE9) is 813 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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