Melanoma-associated antigen D4 (MAGED4)
Homo sapiens — UniProt Q96JG8
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen D4 (MAGED4) is a protein from Homo sapiens identified by UniProt accession Q96JG8, 741 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q96JG8; gene symbol MAGED4.
- Organism: Homo sapiens.
- Length: 741 amino acids.
- Top disease associations (Open Targets): coronary artery disease, gastric adenocarcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen D4 |
|---|---|
| UniProt accession | Q96JG8 |
| Gene | MAGED4 |
| Organism | Homo sapiens |
| Length | 741 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.16
- gastric adenocarcinoma · score 0.07
- neoplasm · score 0.03
- head and neck squamous cell carcinoma · score 0.02
- oral squamous cell carcinoma · score 0.02
- carcinoma · score 0.01
- cancer · score 0.01
- adenocarcinoma · score 0.01
- hepatocellular carcinoma · score 0.01
- melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JG8-F1 | alphafold | PREDICTED | 53.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JG8.
Amino-acid sequence (741 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGED4?
The strongest Open Targets associations for MAGED4 are coronary artery disease, gastric adenocarcinoma, neoplasm, head and neck squamous cell carcinoma and oral squamous cell carcinoma.
How long is the MAGED4 protein?
The Homo sapiens MAGED4 protein (UniProt Q96JG8) is 741 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JG8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JG8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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