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Deubiquitinating protein VCPIP1 (VCPIP1)

Homo sapiens — UniProt Q96JH7

Gene: VCPIP1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Deubiquitinating protein VCPIP1 (VCPIP1) is a protein from Homo sapiens identified by UniProt accession Q96JH7, 1222 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

  • UniProt accession: Q96JH7; gene symbol VCPIP1.
  • Organism: Homo sapiens.
  • Length: 1222 amino acids.
  • Top disease associations (Open Targets): hepatocellular carcinoma, appendicular lean mass and triple-negative breast cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameDeubiquitinating protein VCPIP1
UniProt accessionQ96JH7
GeneVCPIP1
OrganismHomo sapiens
Length1222 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • hepatocellular carcinoma · score 0.07
  • appendicular lean mass · score 0.07
  • triple-negative breast cancer · score 0.06
  • body height · score 0.05
  • body fat percentage · score 0.04
  • visceral adipose tissue measurement · score 0.04
  • adolescent idiopathic scoliosis · score 0.03
  • cancer · score 0.02
  • neoplasm · score 0.01
  • gestational diabetes · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96JH7-F1alphafoldPREDICTED69.38—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JH7.

Amino-acid sequence (1222 residues)

MSQPPPPPPP LPPPPPPPEA PQTPSSLASA AASGGLLKRR DRRILSGSCP DPKCQARLFF PASGSVSIEC TECGQRHEQQ QLLGVEEVTD PDVVLHNLLR NALLGVTGAP KKNTELVKVM GLSNYHCKLL SPILARYGMD KQTGRAKLLR DMNQGELFDC ALLGDRAFLI EPEHVNTVGY GKDRSGSLLY LHDTLEDIKR ANKSQECLIP VHVDGDGHCL VHAVSRALVG RELFWHALRE NLKQHFQQHL ARYQALFHDF IDAAEWEDII NECDPLFVPP EGVPLGLRNI HIFGLANVLH RPIILLDSLS GMRSSGDYSA TFLPGLIPAE KCTGKDGHLN KPICIAWSSS GRNHYIPLVG IKGAALPKLP MNLLPKAWGV PQDLIKKYIK LEEDGGCVIG GDRSLQDKYL LRLVAAMEEV FMDKHGIHPS LVADVHQYFY RRTGVIGVQP EEVTAAAKKA VMDNRLHKCL LCGALSELHV PPEWLAPGGK LYNLAKSTHG QLRTDKNYSF PLNNLVCSYD SVKDVLVPDY GMSNLTACNW CHGTSVRKVR GDGSIVYLDG DRTNSRSTGG KCGCGFKHFW DGKEYDNLPE AFPITLEWGG RVVRETVYWF QYESDSSLNS NVYDVAMKLV TKHFPGEFGS EILVQKVVHT ILHQTAKKNP DDYTPVNIDG AHAQRVGDVQ GQESESQLPT KIILTGQKTK TLHKEELNMS KTERTIQQNI TEQASVMQKR KTEKLKQEQK GQPRTVSPST IRDGPSSAPA TPTKAPYSPT TSKEKKIRIT TNDGRQSMVT LKSSTTFFEL QESIAREFNI PPYLQCIRYG FPPKELMPPQ AGMEKEPVPL QHGDRITIEI LKSKAEGGQS AAAHSAHTVK QEDIAVTGKL SSKELQEQAE KEMYSLCLLA TLMGEDVWSY AKGLPHMFQQ GGVFYSIMKK TMGMADGKHC TFPHLPGKTF VYNASEDRLE LCVDAAGHFP IGPDVEDLVK EAVSQVRAEA TTRSRESSPS HGLLKLGSGG VVKKKSEQLH NVTAFQGKGH SLGTASGNPH LDPRARETSV VRKHNTGTDF SNSSTKTEPS VFTASSSNSE LIRIAPGVVT MRDGRQLDPD LVEAQRKKLQ EMVSSIQASM DRHLRDQSTE QSPSDLPQRK TEVVSSSAKS GSLQTGLPES FPLTGGTENL NTETTDGCVA DALGAAFATR SKAQRGNSVE ELEEMDSQDA EMTNTTEPMD HS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with VCPIP1?

The strongest Open Targets associations for VCPIP1 are hepatocellular carcinoma, appendicular lean mass, triple-negative breast cancer, body height and body fat percentage.

How long is the VCPIP1 protein?

The Homo sapiens VCPIP1 protein (UniProt Q96JH7) is 1222 amino acids long.

Browse: Targets: V · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96JH7
GeneVCPIP1
OrganismHomo sapiens
Length1222
Binders0
Diseases19
View on UniProt