Protein disulfide-isomerase TMX3 (TMX3)
Homo sapiens — UniProt Q96JJ7
Data last refreshed: (UniProt release unknown)
Key facts
Protein disulfide-isomerase TMX3 (TMX3) is a protein from Homo sapiens identified by UniProt accession Q96JJ7, 454 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q96JJ7; gene symbol TMX3.
- Organism: Homo sapiens.
- Length: 454 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, blood protein measurement and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein disulfide-isomerase TMX3 |
|---|---|
| UniProt accession | Q96JJ7 |
| Gene | TMX3 |
| Organism | Homo sapiens |
| Length | 454 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- blood protein measurement · score 0.22
- neurofibrillary tangles measurement · score 0.20
- glioblastoma multiforme · score 0.14
- YKL40 measurement · score 0.13
- inflammatory biomarker measurement · score 0.13
- gut microbiome measurement · score 0.11
- melanoma · score 0.07
- metabolite measurement · score 0.05
- microphthalmia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JJ7-F1 | alphafold | PREDICTED | 85.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JJ7.
Amino-acid sequence (454 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMX3?
The strongest Open Targets associations for TMX3 are breast adenocarcinoma, blood protein measurement, neurofibrillary tangles measurement, glioblastoma multiforme and YKL40 measurement.
How long is the TMX3 protein?
The Homo sapiens TMX3 protein (UniProt Q96JJ7) is 454 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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