HHIP-like protein 1 (HHIPL1)
Homo sapiens — UniProt Q96JK4
Data last refreshed: (UniProt release unknown)
Key facts
HHIP-like protein 1 (HHIPL1) is a protein from Homo sapiens identified by UniProt accession Q96JK4, 782 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q96JK4; gene symbol HHIPL1.
- Organism: Homo sapiens.
- Length: 782 amino acids.
- Top disease associations (Open Targets): coronary artery disease, myocardial infarction and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | HHIP-like protein 1 |
|---|---|
| UniProt accession | Q96JK4 |
| Gene | HHIPL1 |
| Organism | Homo sapiens |
| Length | 782 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.49
- myocardial infarction · score 0.45
- systolic blood pressure · score 0.41
- pulse pressure measurement · score 0.41
- FEV/FVC ratio · score 0.37
- body height · score 0.35
- Myocardial Ischemia · score 0.33
- coronary atherosclerosis · score 0.32
- percutaneous transluminal coronary angioplasty · score 0.32
- cardiovascular disease · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JK4-F1 | alphafold | PREDICTED | 87.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JK4.
Amino-acid sequence (782 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HHIPL1?
The strongest Open Targets associations for HHIPL1 are coronary artery disease, myocardial infarction, systolic blood pressure, pulse pressure measurement and FEV/FVC ratio.
How long is the HHIPL1 protein?
The Homo sapiens HHIPL1 protein (UniProt Q96JK4) is 782 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JK4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JK4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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