Mastermind-like protein 3 (MAML3)
Homo sapiens — UniProt Q96JK9
Data last refreshed: (UniProt release unknown)
Key facts
Mastermind-like protein 3 (MAML3) is a protein from Homo sapiens identified by UniProt accession Q96JK9, 1138 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.
- UniProt accession: Q96JK9; gene symbol MAML3.
- Organism: Homo sapiens.
- Length: 1138 amino acids.
- Top disease associations (Open Targets): cancer, neurodegenerative disease and wellbeing measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mastermind-like protein 3 |
|---|---|
| UniProt accession | Q96JK9 |
| Gene | MAML3 |
| Organism | Homo sapiens |
| Length | 1138 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (122)
Diseases linked to this target (Open Targets).
- cancer · score 0.63
- neurodegenerative disease · score 0.46
- wellbeing measurement · score 0.45
- self reported educational attainment · score 0.45
- body fat percentage · score 0.42
- body mass index · score 0.42
- depressive symptom measurement · score 0.42
- smoking behavior · score 0.39
- type 2 diabetes mellitus · score 0.39
- gastroesophageal reflux disease · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JK9-F1 | alphafold | PREDICTED | 46.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JK9.
Amino-acid sequence (1138 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAML3?
The strongest Open Targets associations for MAML3 are cancer, neurodegenerative disease, wellbeing measurement, self reported educational attainment and body fat percentage.
How long is the MAML3 protein?
The Homo sapiens MAML3 protein (UniProt Q96JK9) is 1138 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.