Ligand-dependent corepressor (LCOR)
Homo sapiens — UniProt Q96JN0
Data last refreshed: (UniProt release unknown)
Key facts
Ligand-dependent corepressor (LCOR) is a protein from Homo sapiens identified by UniProt accession Q96JN0, 433 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q96JN0; gene symbol LCOR.
- Organism: Homo sapiens.
- Length: 433 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and body weight.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ligand-dependent corepressor |
|---|---|
| UniProt accession | Q96JN0 |
| Gene | LCOR |
| Organism | Homo sapiens |
| Length | 433 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- body height · score 0.32
- body weight · score 0.27
- heel bone mineral density · score 0.23
- lean body mass · score 0.15
- fat body mass · score 0.15
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- breast cancer · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JN0-F1 | alphafold | PREDICTED | 55.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JN0.
Amino-acid sequence (433 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCOR?
The strongest Open Targets associations for LCOR are neurodegenerative disease, body height, body weight, heel bone mineral density and lean body mass.
How long is the LCOR protein?
The Homo sapiens LCOR protein (UniProt Q96JN0) is 433 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JN0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JN0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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