Coiled-coil domain-containing protein 136 (CCDC136)
Homo sapiens — UniProt Q96JN2
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 136 (CCDC136) is a protein from Homo sapiens identified by UniProt accession Q96JN2, 1154 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q96JN2; gene symbol CCDC136.
- Organism: Homo sapiens.
- Length: 1154 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, electrocardiography and hypertrophic cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 136 |
|---|---|
| UniProt accession | Q96JN2 |
| Gene | CCDC136 |
| Organism | Homo sapiens |
| Length | 1154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- electrocardiography · score 0.29
- hypertrophic cardiomyopathy · score 0.18
- genetic disorder · score 0.12
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.10
- spermatogenic failure 42 · score 0.07
- spermatogenic failure 72 · score 0.07
- spermatogenic failure 46 · score 0.07
- spermatogenic failure 18 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JN2-F1 | alphafold | PREDICTED | 68.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JN2.
Amino-acid sequence (1154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC136?
The strongest Open Targets associations for CCDC136 are neurodegenerative disease, electrocardiography, hypertrophic cardiomyopathy, genetic disorder and azoospermia.
How long is the CCDC136 protein?
The Homo sapiens CCDC136 protein (UniProt Q96JN2) is 1154 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JN2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JN2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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