Neuralized-like protein 4 (NEURL4)

Homo sapiens — UniProt Q96JN8

Gene: NEURL4Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Neuralized-like protein 4 (NEURL4) is a protein from Homo sapiens identified by UniProt accession Q96JN8, 1562 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

UniProt accession: Q96JN8; gene symbol NEURL4.
Organism: Homo sapiens.
Length: 1562 amino acids.
Top disease associations (Open Targets): Thyroid preparation use measurement, autoimmune disease and neutrophil count.
3D structure: AlphaFold model available.

Target properties

Protein name	Neuralized-like protein 4
UniProt accession	Q96JN8
Gene	NEURL4
Organism	Homo sapiens
Length	1562 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

Thyroid preparation use measurement · score 0.20
autoimmune disease · score 0.17
neutrophil count · score 0.17
lymphocyte count · score 0.17
leukocyte count · score 0.16
endocrine system disease · score 0.14
diabetes mellitus · score 0.14
body height · score 0.14
monocyte percentage of leukocytes · score 0.13
drug use measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96JN8-F1	alphafold	PREDICTED	74.92	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JN8.

Amino-acid sequence (1562 residues)

MAAGSGGSGG SGGGPGPGPG GGGGPSGSGS GPGSNGGLGS GGELHPRTGR LVSLSACGRT ARRQQPGQEF NHGLVLSREP LRDGRVFTVR IDRKVNSWSG SIEIGVTALD PSVLDFPSSA TGLKGGSWVV SGCSVLRDGR SVLEEYGQDL DQLGEGDRVG VERTVAGELR LWVNGRDCGV AATGLPPRVW AVVDLYGKCT QITVLPPEPG FSPPTPIPTP PLEPLAPTED SALAEQGTSA DEAFMVSPAQ ARPETFPNSL ESHNDFANME LSEVVSNTIL SAYNGGLLNV NLSSPPAGEG LGSSGAATSP ILTSNDALLF HEKCGTLIKL SNNNKTAERR RPLDEFNNGV VMTNRPLRDN EMFEIRIDKL VDKWSGSIEI GVTTHNPNSL EYPATMTNLQ SGTIMMSGCG ILTNGKGTRR EYCEFSLDEL QEGDHIGLTR KSNSALHFFI NGIDQGVATP LTPPVVYGVV DLYGMAVKVT IVHNNNHSDR LRRNNAILRA LSPEGALRRA APAAQAEPER LLFHPNCGQK AAITHEGRTA LRPHATDDFN HGVVLSSRAL RDGEVFQVRI DKMVDKWAGS IEIGVTTHNP AYLQLPSTMT NLRSGTWMMT GNGVMHNGTT ILDEYGHNLD RLKAGDTVGV VRREDGTLHF FVNGMTQGPA AWNVPPGVYA VVDLYGQAAQ ATIVDDVEVA PVPEPLPEGN NQVSPSSPSS GAGGSDLRFH QLHGSNAVIT NGGRTALRHN CRSEFNDAIV ISNRALRDGE LFEIVIQKMV DRWSGSIEAG VTAIRPEDLE FPNTMTDIDY DTWMLSGTAI MQDGNTMRNN YGCDLDALGT GARIGMMRTA KGDLHYFING QDQGAACSGL PPGKEVYAVV DLYGQCVQVS ITNATGPMDN SLATSNTATE KSFPLHSPVA GVAHRFHSTC GKNVTLEEDG TRAVRAAGYA HGLVFSTKEL RAEEVFEVKV EELDEKWAGS LRLGLTTLAP GEMGPGAGGG GPGLPPSLPE LRTKTTWMVS SCEVRRDGQL QRMNYGRNLE RLGVGSRVGV RRGADDTMHI LVDGEDMGPA ATGIAKNVWA VLDLYGPVRG VSIVSSTRLE ESEGTQPPSP SSDTGSEGEE DDEGEEHGLG GQNEVGIIPT TLEFLENHGK NILLSNGNRT ATRVASYNQG IVVINQPLVP QLLVQVRIDF LNRQWTSSLV LGVITCAPER LNFPASACAL KRAAWLLRGR GVFHNGLKIC EKFGPNLDTC PEGTILGLRL DSSGGLHLHV NGVDQGVAVP DVPQPCHALV DLYGQCEQVT IVNPEPGAAS GKSAGTQGDM EKADMVDGIK ESVCWGPPPA ASPLKSCEYH ALCSRFQELL LLPEDYFMPP PKRSLCYCES CRKLRGDEAH RRRGEPPREY ALPFGWCRFN LRVNPRLEAG TLTKKWHMAY HGSNVAAVRR VLDRGELGAG TASILSCRPL KGEPGVGFEE PGENCAPPRE EQPPPVLLSP SLQYAGAETL ASKVQFRDPK SQRTHQAQVA FQVCVRPGSY TPGPPSAALG EPPDPHFSPA ELEWVTKEKG ATLLCALLVR VE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NEURL4?

The strongest Open Targets associations for NEURL4 are Thyroid preparation use measurement, autoimmune disease, neutrophil count, lymphocyte count and leukocyte count.

How long is the NEURL4 protein?

The Homo sapiens NEURL4 protein (UniProt Q96JN8) is 1562 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q96JN8 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q96JN8 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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