Protein SERAC1 (SERAC1)
Homo sapiens — UniProt Q96JX3
Data last refreshed: (UniProt release unknown)
Key facts
Protein SERAC1 (SERAC1) is a protein from Homo sapiens identified by UniProt accession Q96JX3, 654 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q96JX3; gene symbol SERAC1.
- Organism: Homo sapiens.
- Length: 654 amino acids.
- Top disease associations (Open Targets): 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome, MEGDEL syndrome and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein SERAC1 |
|---|---|
| UniProt accession | Q96JX3 |
| Gene | SERAC1 |
| Organism | Homo sapiens |
| Length | 654 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome · score 0.82
- MEGDEL syndrome · score 0.64
- genetic disorder · score 0.41
- Dystonia · score 0.37
- Leigh syndrome · score 0.37
- Hypoglycemia · score 0.37
- mitochondrial oxidative phosphorylation disorder · score 0.27
- SERAC1-related neurological disorder · score 0.27
- lipoprotein A measurement · score 0.26
- Seizure · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JX3-F1 | alphafold | PREDICTED | 78.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JX3.
Amino-acid sequence (654 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERAC1?
The strongest Open Targets associations for SERAC1 are 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome, MEGDEL syndrome, genetic disorder, Dystonia and Leigh syndrome.
How long is the SERAC1 protein?
The Homo sapiens SERAC1 protein (UniProt Q96JX3) is 654 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JX3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JX3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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