Protein maelstrom homolog (MAEL)
Homo sapiens — UniProt Q96JY0
Data last refreshed: (UniProt release unknown)
Key facts
Protein maelstrom homolog (MAEL) is a protein from Homo sapiens identified by UniProt accession Q96JY0, 434 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.
- UniProt accession: Q96JY0; gene symbol MAEL.
- Organism: Homo sapiens.
- Length: 434 amino acids.
- Top disease associations (Open Targets): male infertility, cortical surface area measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein maelstrom homolog |
|---|---|
| UniProt accession | Q96JY0 |
| Gene | MAEL |
| Organism | Homo sapiens |
| Length | 434 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (133)
Diseases linked to this target (Open Targets).
- male infertility · score 0.33
- cortical surface area measurement · score 0.32
- brain measurement · score 0.32
- neuroimaging measurement · score 0.26
- cortical thickness · score 0.25
- cutaneous melanoma · score 0.15
- neutrophil percentage of leukocytes · score 0.13
- sex hormone-binding globulin measurement · score 0.11
- breast adenocarcinoma · score 0.09
- neutrophil count · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96JY0-F1 | alphafold | PREDICTED | 72.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96JY0.
Amino-acid sequence (434 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAEL?
The strongest Open Targets associations for MAEL are male infertility, cortical surface area measurement, brain measurement, neuroimaging measurement and cortical thickness.
How long is the MAEL protein?
The Homo sapiens MAEL protein (UniProt Q96JY0) is 434 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96JY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96JY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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