About Zinc finger protein 514
Zinc finger protein 514 (ZNF514) is a protein
from Homo sapiens identified by UniProt accession
Q96K75, 400 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Zinc finger protein 514 |
| UniProt accession | Q96K75 |
| Gene | ZNF514 |
| Organism | Homo sapiens |
| Length | 400 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.05
- body height · score 0.02
- calcium measurement · score 0.02
- colorectal cancer · score 0.01
- psoriasis · score 0.01
- chronic kidney disease · score 0.00
- carcinoma · score 0.00
- nicotine dependence · score 0.00
- pancreatic ductal adenocarcinoma · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96K75-F1 | alphafold | PREDICTED | 66.12 | — |
Amino-acid sequence (400 residues)
MTFEDVAVEF SQWEWGQLNP AQKDLYREVM LENFRNLAIL GLLVSKPYVI CQLEEGGEPF MVEREISTGA HSDWKRRSKS KESMPSWGIS KEELFQVVSV EKHIQDVLQF SKLKAACGCD GQLEMQQIKQ ERHLKQMSTI HKSATTLSRD YKWNGFGRSL GLRSVLVNQH SILMGEGSYK CDTEFRQTLG GNNSQRTHPE KKSCKCNECG KSFHFQSELR RHQRCHTGEK PYECSDCGRA FGHISSLIKH QRTHTGEKPY ECSECGRAFS QSSSLVLHYR FHTGEKPYKC NECGRAFGHT SSLIKHQRTH TGEKPYECRE CGRTFSQSSS LIVHYRFHTG EKPYKCNKCG RAFSQSSSLT QHYRFHTGEK PYKCNECGRA FAHTASLIKH QRSHAGKKTL
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