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Zinc finger protein 521 (ZNF521)

Homo sapiens — UniProt Q96K83

Gene: ZNF521Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 521 (ZNF521) is a protein from Homo sapiens identified by UniProt accession Q96K83, 1311 residues long. MolForge cross-references it against 0 known binders and 219 disease associations.

  • UniProt accession: Q96K83; gene symbol ZNF521.
  • Organism: Homo sapiens.
  • Length: 1311 amino acids.
  • Top disease associations (Open Targets): body height, neurodegenerative disease and balding measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 521
UniProt accessionQ96K83
GeneZNF521
OrganismHomo sapiens
Length1311 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (219)

Diseases linked to this target (Open Targets).

  • body height · score 0.50
  • neurodegenerative disease · score 0.43
  • balding measurement · score 0.41
  • mathematical ability · score 0.40
  • self reported educational attainment · score 0.40
  • chronotype measurement · score 0.40
  • pancreatic ductal adenocarcinoma · score 0.37
  • pancreatic carcinoma · score 0.37
  • prostate adenocarcinoma · score 0.37
  • gastric carcinoma · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96K83-F1alphafoldPREDICTED60.79—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96K83.

Amino-acid sequence (1311 residues)

MSRRKQAKPR SLKDPNCKLE DKTEDGEALD CKKRPEDGEE LEDEAVHSCD SCLQVFESLS DITEHKINQC QLTDGVDVED DPTCSWPASS PSSKDQTSPS HGEGCDFGEE EGGPGLPYPC QFCDKSFSRL SYLKHHEQSH SDKLPFKCTY CSRLFKHKRS RDRHIKLHTG DKKYHCSECD AAFSRSDHLK IHLKTHTSNK PYKCAICRRG FLSSSSLHGH MQVHERNKDG SQSGSRMEDW KMKDTQKCSQ CEEGFDFPED LQKHIAECHP ECSPNEDRAA LQCVYCHELF VEETSLMNHM EQVHSGEKKN SCSICSESFH TVEELYSHMD SHQQPESCNH SNSPSLVTVG YTSVSSTTPD SNLSVDSSTM VEAAPPIPKS RGRKRAAQQT PDMTGPSSKQ AKVTYSCIYC NKQLFSSLAV LQIHLKTMHL DKPEQAHICQ YCLEVLPSLY NLNEHLKQVH EAQDPGLIVS AMPAIVYQCN FCSEVVNDLN TLQEHIRCSH GFANPAAKDS NAFFCPHCYM GFLTDSSLEE HIRQVHCDLS GSRFGSPVLG TPKEPVVEVY SCSYCTNSPI FNSVLKLNKH IKENHKNIPL ALNYIHNGKK SRALSPLSPV AIEQTSLKMM QAVGGAPARP TGEYICNQCG AKYTSLDSFQ THLKTHLDTV LPKLTCPQCN KEFPNQESLL KHVTIHFMIT STYYICESCD KQFTSVDDLQ KHLLDMHTFV FFRCTLCQEV FDSKVSIQLH LAVKHSNEKK VYRCTSCNWD FRNETDLQLH VKHNHLENQG KVHKCIFCGE SFGTEVELQC HITTHSKKYN CKFCSKAFHA IILLEKHLRE KHCVFETKTP NCGTNGASEQ VQKEEVELQT LLTNSQESHN SHDGSEEDVD TSEPMYGCDI CGAAYTMETL LQNHQLRDHN IRPGESAIVK KKAELIKGNY KCNVCSRTFF SENGLREHMQ THLGPVKHYM CPICGERFPS LLTLTEHKVT HSKSLDTGNC RICKMPLQSE EEFLEHCQMH PDLRNSLTGF RCVVCMQTVT STLELKIHGT FHMQKTGNGS AVQTTGRGQH VQKLYKCASC LKEFRSKQDL VKLDINGLPY GLCAGCVNLS KSASPGINVP PGTNRPGLGQ NENLSAIEGK GKVGGLKTRC SSCNVKFESE SELQNHIQTI HRELVPDSNS TQLKTPQVSP MPRISPSQSD EKKTYQCIKC QMVFYNEWDI QVHVANHMID EGLNHECKLC SQTFDSPAKL QCHLIEHSFE GMGGTFKCPV CFTVFVQANK LQQHIFSAHG QEDKIYDCTQ CPQKFFFQTE LQNHTMTQHS S

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF521?

The strongest Open Targets associations for ZNF521 are body height, neurodegenerative disease, balding measurement, mathematical ability and self reported educational attainment.

How long is the ZNF521 protein?

The Homo sapiens ZNF521 protein (UniProt Q96K83) is 1311 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ96K83
GeneZNF521
OrganismHomo sapiens
Length1311
Binders0
Diseases219
View on UniProt