BTB/POZ domain-containing protein 6 (BTBD6)
Homo sapiens — UniProt Q96KE9
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein 6 (BTBD6) is a protein from Homo sapiens identified by UniProt accession Q96KE9, 538 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q96KE9; gene symbol BTBD6.
- Organism: Homo sapiens.
- Length: 538 amino acids.
- Top disease associations (Open Targets): platelet count, erythrocyte count and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein 6 |
|---|---|
| UniProt accession | Q96KE9 |
| Gene | BTBD6 |
| Organism | Homo sapiens |
| Length | 538 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- platelet count · score 0.28
- erythrocyte count · score 0.23
- mean corpuscular volume · score 0.23
- mean corpuscular hemoglobin · score 0.21
- platelet component distribution width · score 0.18
- mean platelet volume · score 0.17
- mean corpuscular hemoglobin concentration · score 0.17
- red blood cell density measurement · score 0.16
- platelet crit · score 0.13
- total blood protein measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96KE9-F1 | alphafold | PREDICTED | 81.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96KE9.
Amino-acid sequence (538 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BTBD6?
The strongest Open Targets associations for BTBD6 are platelet count, erythrocyte count, mean corpuscular volume, mean corpuscular hemoglobin and platelet component distribution width.
How long is the BTBD6 protein?
The Homo sapiens BTBD6 protein (UniProt Q96KE9) is 538 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96KE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96KE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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