Apoptosis-stimulating of p53 protein 1 (PPP1R13B)
Homo sapiens — UniProt Q96KQ4
Data last refreshed: (UniProt release unknown)
Key facts
Apoptosis-stimulating of p53 protein 1 (PPP1R13B) is a protein from Homo sapiens identified by UniProt accession Q96KQ4, 1090 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q96KQ4; gene symbol PPP1R13B.
- Organism: Homo sapiens.
- Length: 1090 amino acids.
- Top disease associations (Open Targets): schizophrenia, attention deficit hyperactivity disorder and alcohol use disorder measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Apoptosis-stimulating of p53 protein 1 |
|---|---|
| UniProt accession | Q96KQ4 |
| Gene | PPP1R13B |
| Organism | Homo sapiens |
| Length | 1090 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.38
- attention deficit hyperactivity disorder · score 0.31
- alcohol use disorder measurement · score 0.31
- risk-taking behaviour · score 0.29
- low grade glioma · score 0.29
- anorexia nervosa · score 0.29
- esophageal cancer · score 0.28
- breast adenocarcinoma · score 0.28
- lung adenocarcinoma · score 0.28
- squamous cell lung carcinoma · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96KQ4-F1 | alphafold | PREDICTED | 59.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96KQ4.
Amino-acid sequence (1090 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R13B?
The strongest Open Targets associations for PPP1R13B are schizophrenia, attention deficit hyperactivity disorder, alcohol use disorder measurement, risk-taking behaviour and low grade glioma.
How long is the PPP1R13B protein?
The Homo sapiens PPP1R13B protein (UniProt Q96KQ4) is 1090 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96KQ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96KQ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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