Fc receptor-like protein 1 (FCRL1)
Homo sapiens — UniProt Q96LA6
Data last refreshed: (UniProt release unknown)
Key facts
Fc receptor-like protein 1 (FCRL1) is a protein from Homo sapiens identified by UniProt accession Q96LA6, 429 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q96LA6; gene symbol FCRL1.
- Organism: Homo sapiens.
- Length: 429 amino acids.
- Top disease associations (Open Targets): blood protein measurement, neurodegenerative disease and coronary artery disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fc receptor-like protein 1 |
|---|---|
| UniProt accession | Q96LA6 |
| Gene | FCRL1 |
| Organism | Homo sapiens |
| Length | 429 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.38
- neurodegenerative disease · score 0.16
- coronary artery disease · score 0.16
- Graves disease · score 0.06
- primary biliary cirrhosis · score 0.05
- diffuse large B-cell lymphoma · score 0.05
- rheumatoid arthritis · score 0.05
- autoantibody measurement · score 0.04
- Rheumatoid arthritis · score 0.04
- systemic lupus erythematosus · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LA6-F1 | alphafold | PREDICTED | 75.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LA6.
Amino-acid sequence (429 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FCRL1?
The strongest Open Targets associations for FCRL1 are blood protein measurement, neurodegenerative disease, coronary artery disease, Graves disease and primary biliary cirrhosis.
How long is the FCRL1 protein?
The Homo sapiens FCRL1 protein (UniProt Q96LA6) is 429 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LA6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LA6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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