CCR4-NOT transcription complex subunit 6-like (CNOT6L)
Homo sapiens — UniProt Q96LI5
Data last refreshed: (UniProt release unknown)
Key facts
CCR4-NOT transcription complex subunit 6-like (CNOT6L) is a protein from Homo sapiens identified by UniProt accession Q96LI5, 555 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q96LI5; gene symbol CNOT6L.
- Organism: Homo sapiens.
- Length: 555 amino acids.
- Top disease associations (Open Targets): body fat percentage, brain volume measurement and acute myeloid leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CCR4-NOT transcription complex subunit 6-like |
|---|---|
| UniProt accession | Q96LI5 |
| Gene | CNOT6L |
| Organism | Homo sapiens |
| Length | 555 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.36
- brain volume measurement · score 0.35
- acute myeloid leukemia · score 0.26
- low grade glioma · score 0.25
- breast adenocarcinoma · score 0.25
- urinary bladder cancer · score 0.23
- head and neck squamous cell carcinoma · score 0.23
- squamous cell lung carcinoma · score 0.23
- lung adenocarcinoma · score 0.23
- pancreatic adenocarcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LI5-F1 | alphafold | PREDICTED | 90.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LI5.
Amino-acid sequence (555 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNOT6L?
The strongest Open Targets associations for CNOT6L are body fat percentage, brain volume measurement, acute myeloid leukemia, low grade glioma and breast adenocarcinoma.
How long is the CNOT6L protein?
The Homo sapiens CNOT6L protein (UniProt Q96LI5) is 555 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LI5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LI5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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