UBX domain-containing protein 10 (UBXN10)
Homo sapiens — UniProt Q96LJ8
Data last refreshed: (UniProt release unknown)
Key facts
UBX domain-containing protein 10 (UBXN10) is a protein from Homo sapiens identified by UniProt accession Q96LJ8, 280 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q96LJ8; gene symbol UBXN10.
- Organism: Homo sapiens.
- Length: 280 amino acids.
- Top disease associations (Open Targets): isolated asymptomatic elevation of creatine phosphokinase, pentosuria and Barrett's esophagus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UBX domain-containing protein 10 |
|---|---|
| UniProt accession | Q96LJ8 |
| Gene | UBXN10 |
| Organism | Homo sapiens |
| Length | 280 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- isolated asymptomatic elevation of creatine phosphokinase · score 0.06
- pentosuria · score 0.05
- Barrett's esophagus · score 0.05
- myopathy due to calsequestrin and SERCA1 protein overload · score 0.04
- metabolic myopathy due to lactate transporter defect · score 0.04
- esophageal adenocarcinoma · score 0.03
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- squamous cell carcinoma · score 0.02
- neoplasm · score 0.01
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LJ8-F1 | alphafold | PREDICTED | 68.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LJ8.
Amino-acid sequence (280 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBXN10?
The strongest Open Targets associations for UBXN10 are isolated asymptomatic elevation of creatine phosphokinase, pentosuria, Barrett's esophagus, myopathy due to calsequestrin and SERCA1 protein overload and metabolic myopathy due to lactate transporter defect.
How long is the UBXN10 protein?
The Homo sapiens UBXN10 protein (UniProt Q96LJ8) is 280 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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