Spermatogenesis-associated protein 32 (SPATA32)
Homo sapiens — UniProt Q96LK8
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-associated protein 32 (SPATA32) is a protein from Homo sapiens identified by UniProt accession Q96LK8, 384 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q96LK8; gene symbol SPATA32.
- Organism: Homo sapiens.
- Length: 384 amino acids.
- Top disease associations (Open Targets): asthma, lymphocyte count and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-associated protein 32 |
|---|---|
| UniProt accession | Q96LK8 |
| Gene | SPATA32 |
| Organism | Homo sapiens |
| Length | 384 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- asthma · score 0.38
- lymphocyte count · score 0.31
- protein measurement · score 0.28
- myeloid white cell count · score 0.26
- atopic asthma · score 0.24
- respiratory system disease · score 0.24
- platelet count · score 0.23
- seasonal allergic rhinitis · score 0.22
- platelet crit · score 0.15
- creatinine measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LK8-F1 | alphafold | PREDICTED | 42.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LK8.
Amino-acid sequence (384 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA32?
The strongest Open Targets associations for SPATA32 are asthma, lymphocyte count, protein measurement, myeloid white cell count and atopic asthma.
How long is the SPATA32 protein?
The Homo sapiens SPATA32 protein (UniProt Q96LK8) is 384 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LK8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LK8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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