Protein phosphatase 1 regulatory subunit 36 (PPP1R36)
Homo sapiens — UniProt Q96LQ0
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 36 (PPP1R36) is a protein from Homo sapiens identified by UniProt accession Q96LQ0, 422 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q96LQ0; gene symbol PPP1R36.
- Organism: Homo sapiens.
- Length: 422 amino acids.
- Top disease associations (Open Targets): cup-to-disc ratio measurement, optic disc size measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 36 |
|---|---|
| UniProt accession | Q96LQ0 |
| Gene | PPP1R36 |
| Organism | Homo sapiens |
| Length | 422 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- cup-to-disc ratio measurement · score 0.20
- optic disc size measurement · score 0.16
- Red cell distribution width · score 0.16
- optic disc area measurement · score 0.15
- optic cup area measurement · score 0.15
- appendicular lean mass · score 0.14
- mean corpuscular hemoglobin · score 0.12
- testosterone measurement · score 0.09
- platelet count · score 0.08
- high density lipoprotein cholesterol measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LQ0-F1 | alphafold | PREDICTED | 68.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LQ0.
Amino-acid sequence (422 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R36?
The strongest Open Targets associations for PPP1R36 are cup-to-disc ratio measurement, optic disc size measurement, Red cell distribution width, optic disc area measurement and optic cup area measurement.
How long is the PPP1R36 protein?
The Homo sapiens PPP1R36 protein (UniProt Q96LQ0) is 422 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.