UPF0739 protein C1orf74 (C1orf74)
Homo sapiens — UniProt Q96LT6
Data last refreshed: (UniProt release unknown)
Key facts
UPF0739 protein C1orf74 (C1orf74) is a protein from Homo sapiens identified by UniProt accession Q96LT6, 269 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q96LT6; gene symbol C1orf74.
- Organism: Homo sapiens.
- Length: 269 amino acids.
- Top disease associations (Open Targets): systolic blood pressure, Orofacial cleft and cleft lip.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0739 protein C1orf74 |
|---|---|
| UniProt accession | Q96LT6 |
| Gene | C1orf74 |
| Organism | Homo sapiens |
| Length | 269 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.16
- Orofacial cleft · score 0.16
- cleft lip · score 0.15
- Cleft palate · score 0.14
- lung adenocarcinoma · score 0.07
- inflammatory bowel disease · score 0.06
- body mass index · score 0.05
- hip circumference · score 0.03
- progranulin measurement · score 0.03
- osteosarcoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LT6-F1 | alphafold | PREDICTED | 90.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LT6.
Amino-acid sequence (269 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1orf74?
The strongest Open Targets associations for C1orf74 are systolic blood pressure, Orofacial cleft, cleft lip, Cleft palate and lung adenocarcinoma.
How long is the C1orf74 protein?
The Homo sapiens C1orf74 protein (UniProt Q96LT6) is 269 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LT6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LT6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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