Zinc finger protein 354B (ZNF354B)
Homo sapiens — UniProt Q96LW1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 354B (ZNF354B) is a protein from Homo sapiens identified by UniProt accession Q96LW1, 612 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q96LW1; gene symbol ZNF354B.
- Organism: Homo sapiens.
- Length: 612 amino acids.
- Top disease associations (Open Targets): refractive error, Abnormality of refraction and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 354B |
|---|---|
| UniProt accession | Q96LW1 |
| Gene | ZNF354B |
| Organism | Homo sapiens |
| Length | 612 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- refractive error · score 0.15
- Abnormality of refraction · score 0.12
- inflammatory bowel disease · score 0.09
- PHF-tau measurement · score 0.03
- infection · score 0.01
- infect · score 0.01
- small cell lung carcinoma · score 0.00
- colitis · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q96LW1-F1 | alphafold | PREDICTED | 67.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q96LW1.
Amino-acid sequence (612 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF354B?
The strongest Open Targets associations for ZNF354B are refractive error, Abnormality of refraction, inflammatory bowel disease, PHF-tau measurement and infection.
How long is the ZNF354B protein?
The Homo sapiens ZNF354B protein (UniProt Q96LW1) is 612 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q96LW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q96LW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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